GeneIII® L-Ergothioneine 30mg
GeneIII® delivers 30mg of ultra-pure, clinically studied L-Ergothioneine to support restorative sleep, steady energy, cognitive wellness, and healthy aging at the cellular level.*
Unlike ordinary antioxidants, L-Ergothioneine is actively transported into your cells through the OCTN1 transporter and accumulates in areas of high oxidative stress like the brain, liver, and eyes.
- 99.99% ultra-pure L-Ergothioneine
- Clinically studied 30mg dosage
- Supports sleep, energy, and cognitive health
- Third-party tested, vegan-friendly, no unnecessary fillers
- FDA-notified GRAS ingredient
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Product Details
L-Ergothioneine is a unique antioxidant naturally found in certain foods like mushrooms, but what makes it remarkable is that the human body has a dedicated transporter, OCTN1, specifically designed to absorb and retain it.
Research suggests L-Ergothioneine accumulates in areas exposed to high oxidative stress, including the brain, liver, eyes, and mitochondria, where it helps support cellular resilience and long-term wellness.
GeneIII® delivers 30mg of ultra-pure L-Ergothioneine per capsule, produced through patented fermentation and refined to 99.99% purity (the highest on the market!) for exceptional consistency and quality.
Key ingredients
Each capsule contains pure L-Ergothioneine (EGT). GeneIII is a science-backed, patented, award-winning, pure and vegan-friendly EGT supplement to support your long-term health and wellness.
No unnecessary fillers, artificial colors, or preservatives.
Why Ergothioneine?
L-Ergothioneine is a rare amino acid-derived antioxidant naturally found in small amounts in certain foods like mushrooms. What makes it unique is that the human body has a specific transporter, OCTN1, designed to absorb and retain it.
Research suggests L-Ergothioneine accumulates in tissues exposed to high levels of oxidative stress, where it helps support cellular protection and mitochondrial health.
Because the body actively retains it, many researchers consider L-Ergothioneine fundamentally different from conventional antioxidants.
How to use
Take 1-2 capsules daily, with or without a meal.
For best results, use consistently for at least 6–8 weeks.
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Measurable Improvements Within 30 Days*
*Based on a 30-day clinical study using biomarker and self-reported outcome measures. Results may vary.
Whole-Body Wellness
Clinical Study Results
Energy & Fatigue
Participants reported measurable improvements after 30 days of GeneIII L-Ergothioneine supplementation:
- 39% improvement in overall physical function, including reduced fatigue and improved recovery*
- 51.56% improvement in daytime energy levels*
- Improvements in sleep quality and how participants felt the next day*
Ovarian Health
In a 3-cycle clinical observation, participants showed measurable changes in markers associated with ovarian function:
- AMH levels improved (from 1.79 to 2.47 ng/mL after 3 cycles)*
- Significant improvements in cycle regularity and menstrual comfort*
- Reductions in symptoms commonly associated with hormonal imbalance*
Liver Health
In a 30-day clinical trial, participants taking 60mg of GeneIII L-Ergothioneine daily showed:
- Around 20% reduction in AST levels associated with liver stress*
- Around 21% reduction in ALT levels*
- 18% reduction in GGT levels after 30 days*
- Improvements in physical recovery and fatigue*
Postpartum Health
A placebo-controlled human clinical trial found that postpartum participants taking GeneIII L-Ergothioneine for 30 days experienced significant improvements compared to placebo
- 35.94% improvement in overall quality of life (SF-36)*
- 37.43% increase in daily vitality*
- 27.78% reduction in physical fatigue*
*Based on findings from registered human clinical studies and observational research on GeneIII L-Ergothioneine. Results may vary.
Backed by Rigorous Science and Uncompromising Standards
At GeneIII, we are dedicated to the highest standards in science, supplement quality and safety.
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$15M+ invested in clinical research
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Pure & patented L-EGT ingredient
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Highest-standard manufacturing
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Every batch independently tested
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FDA GRAS favorable review
Better Aging Starts at the Cellular Level
Deep, Restorative Sleep
Your body does its deepest repair at night. L-Ergothioneine is transported into cells involved in recovery and stress response, supporting more restful, uninterrupted sleep. In our 30-day clinical trial, 51% of participants reported fewer sleep disturbances.*
Improved Energy Levels
Energy without the crash. By protecting cells from everyday oxidative stress, L-Ergothioneine supports your mitochondria, the engines of cellular energy, helping you sustain steady focus and vitality throughout the day, no stimulants required.*
Cognitive Performance
Clarity starts at the cellular level. L-Ergothioneine accumulates in the brain through OCTN1, your body's dedicated transporter, where it helps support cognitive function, focus, and long-term brain health for years to come.*
Frequently Asked Questions
What is L-Ergothioneine?
L-Ergothioneine (L-EGT) is a rare amino acid and powerful antioxidant naturally found in mushrooms. Unlike most antioxidants, your body has a dedicated transporter called OCTN1 specifically designed to absorb and retain it in areas with high oxidative stress, including the brain, liver, eyes, and skin.
Research suggests L-Ergothioneine may play an important role in supporting cellular health, healthy aging, cognitive function, and resilience against everyday oxidative stress.
Can't I just get L-Ergothioneine from food?
You can, but typically only in very small amounts.
L-Ergothioneine is primarily found in certain mushrooms, though levels vary significantly depending on species, growing conditions, storage, and preparation. To reach the amount found in a single GeneIII capsule, you may need to consume several hundred grams of mushrooms daily.
GeneIII uses a patented fermentation-based process to produce highly pure L-Ergothioneine with consistent potency and quality in every capsule.
How do I take GeneIII L-EGT?
Take 1-2 capsules daily, with or without food.
L-Ergothioneine is designed to build up in the body over time through the OCTN1 transporter system. Consistency matters more than timing, so we recommend taking it daily as part of your long-term wellness routine.
Why should I take GeneIII L-EGT?
Modern life exposes our cells to constant oxidative stress from aging, poor sleep, environmental factors, and everyday metabolism.
L-Ergothioneine helps support the body’s natural defense systems at the cellular level. GeneIII L-EGT is designed to support healthy aging, cognitive health, energy production, sleep quality, and overall cellular resilience.
What makes GeneIII different is our commitment to purity, research, and quality. We produce our own L-Ergothioneine using patented biotechnology and achieve 99.99% purity, backed by rigorous testing and registered human clinical research.
When will I feel something?
Everyone’s experience is different. Some people report noticing improvements in areas like energy, sleep quality, or overall well-being within a few weeks of consistent use, while others may notice more gradual changes over time.
Because L-Ergothioneine works at the cellular level, it is best thought of as a long-term investment in healthy aging and resilience, rather than a quick stimulant or temporary boost.
