The Science Behind GeneIII
Most supplement brands buy ingredients from third-party suppliers. At GeneIII, we produce our own patented L-Ergothioneine using precision fermentation, then study it through human clinical research in partnership with leading scientists in the field.
Below is the process behind how our L-Ergothioneine is made.
1. Strain Selection
We begin with a carefully optimized strain of microorganism that naturally knows how to produce ergothioneine.
Using biotechnology, we help this natural process work far more efficiently and consistently than relying on mushrooms or unpredictable agricultural sources.
Why this matters:
- Mushrooms naturally contain only small amounts of ergothioneine
- Levels vary dramatically depending on growing conditions and soil quality
- Extracts may contain unwanted compounds and inconsistencies
2. Precision Fermentation
Using a controlled fermentation process (similar to how foods like yogurt are made), the microorganisms naturally produce L-Ergothioneine. This method ensures consistency from batch to batch.
Every part of the environment is tightly monitored:
- Temperature
- pH
- Oxygen
- Nutrients
- Purity
3. Multi-Step Purification
We carefully isolate and purify the EGT through multiple filtration and refinement steps. This process removes impurities and other unwanted byproducts. The final result: 99.99% pure EGT is the highest purity on the market.
At first glance, 98% or 99% may seem similar, but that difference means up to 200 times more impurities. Higher purity means a cleaner, more consistent ingredient.
4. Encapsulation
From ingredient to capsule, every step happens under our control. That means consistent quality, complete traceability, and a product you can trust every time.
5. Testing
FDA-Reviewed GRAS Ingredient
Our L-Ergothioneine ingredient has undergone a comprehensive FDA GRAS (Generally Recognized As Safe) notification process for use in food applications.
As part of this process, extensive documentation was reviewed, including:
- Manufacturing methods
- Purity specifications
- Stability testing
- Toxicology data
- Dietary exposure assessments
- Safety studies
Insert link to FDA website
Allergen + Contaminant Testing
Every batch undergoes extensive testing for:
- Purity
- Heavy metals
- Microbiological safety
- Residual solvents
- Stability
- Common allergens
Our ingredient is tested for long-term stability and manufactured under current Good Manufacturing Practices (cGMP) in the USA.
Third-Party Testing
Our L-Ergothioneine ingredient is independently tested by internationally recognized third-party laboratories, including SGS and Eurofins, to verify quality and consistency. All testing is conducted to help ensure the ingredient meets rigorous quality and safety standards.
