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Glass beaker of purified L-ergothioneine solution on a laboratory bench
Scientist in lab gloves operating a fermentation bioreactor

At GeneIII,
science comes before everything.

We develop high-purity L-Ergothioneine through proprietary fermentation, combining scientific research with advanced biotechnology.

In-House Manufacturing

We produce our own L-Ergothioneine in-house, giving us complete control over purity, consistency, and traceability.

The GeneIII Difference

Illustration of ergothioneine molecules entering a cell through the OCTN1 transporter

1909

First discovered by French chemist Charles Tanret

2005

Researchers discovered the body’s dedicated transporter for EGT (OCTN1), revealing that the body actively absorbs and retains it.

2021 

GeneIII introduced a patented precision fermentation process to produce EGT at 99.99% purity – the highest on the market. 

Purification column processing ergothioneine in a laboratory

01. Proprietary Strain Development

Our proprietary production strain was developed specifically to produce high-purity L-Ergothioneine, forming the foundation of our fermentation technology.

02.Precision Fermentation

Our patented fermentation process creates the ideal production environment by carefully controlling temperature, pH, oxygen, and nutrients.

03.Multi-Step Purification

Multiple purification steps remove impurities, producing 99.99% pure L-Ergothioneine— the highest purity currently available on the market.

Quality-control testing equipment with rows of test tubes in a laboratory Open white capsule with pure ergothioneine powder

04. Encapsulation

Our purified L-Ergothioneine is encapsulated and bottled in the USA in cGMP-compliant facilities that follow rigorous manufacturing and quality standards.

Rigorous Safety Standards

FDA-Reviewed
GRAS Ingredient

Third-Party Testing

Our L-Ergothioneine has received an FDA “No Questions” Letter for its GRAS notification, supporting its intended use as a food ingredient.

See our FDA GRAS notice here.

Every batch is verified by independent third-party laboratories to ensure consistent quality, purity, and safety.

Identity Confirmed
99.99% Purity
Heavy Metal Screening
Microbial Safety
Potency Verified

Certificates of Analysis (COAs) are available upon request.

Scientific Collaborations

Our research includes collaborations with internationally recognized scientists and research institutions, including Professor Barry Halliwell and Temasek Life Sciences Laboratory.

Prof. Barry Halliwell

World-renowned expert in oxidative stress and antioxidant research.

Advancing life science research for better health outcomes.

Award-Winning

30+ International Patents

Highest Purity

pH

Oxygen

Temperature

99.99% Purity

Up to 200× fewer impurities than 98%

High Dosage

Third-Party Tested

Made in the USA

01.

02.

THIRD-PARTY VERIFIED

PASS

FAIL

Clinical Studies

GeneIII’s L-Ergothioneine has been evaluated in investigator-initiated human clinical trials registered with the World Health Organization’s International Clinical Trials Registry Platform (ICTRP).

See our clinical studies here.

Liver Health

Sleep Quality

Healthy Aging

Women’s Health

Glass beaker of purified L-ergothioneine solution on a laboratory bench

Why GeneIII

At GeneIII,
science comes before everything.

We develop high-purity L-Ergothioneine (EGT) through proprietary fermentation, combining scientific research with advanced biotechnology.

1909

First discovered by French chemist Charles Tanret

Archival photo of scientists conducting early ergothioneine research

2005A Major Breakthrough

Researchers discovered the body’s dedicated transporter for EGT (OCTN1), revealing that the body actively absorbs and retains it.

Illustration of ergothioneine molecules entering a cell through the OCTN1 transporter

2021The GeneIII Breakthrough

GeneIII introduced a patented precision fermentation process to produce EGT at 99.99% purity – the highest on the market. 

In-House Manufacturing

We produce our own EGT in-house, giving us complete control over purity, consistency, and traceability.

The GeneIII Difference

Precision
Fermentation

Our patented fermentation process creates the ideal production environment by carefully controlling:

Proprietary Strain Development

Our proprietary production strain was developed specifically to produce high-purity L-Ergothioneine, forming the foundation of our fermentation technology.

Award-Winning

Highest Purity

30+ International Patents

pH

Oxygen

Temperature

01

03

04

Purification column processing ergothioneine in a laboratory Scientist in lab gloves operating a fermentation bioreactor
Quality-control testing equipment with rows of test tubes in a laboratory

Multi-Step Purification

Multiple purification steps remove impurities, producing 99.99% pure L-Ergothioneine— the highest purity available.

Encapsulation

Our purified EGT is encapsulated and bottled in the USA in GMP-compliant facilities that follow rigorous manufacturing and quality standards.

99.99% Purity

Up to 200× fewer impurities than 98%

Open white capsule with pure ergothioneine powder

Rigorous Safety
Standards

FDA-Reviewed GRAS Ingredient

Third-party Testing

Our L-Ergothioneine has received an FDA “No Questions” Letter for its GRAS notification, supporting its intended use as a food ingredient.

See our FDA GRAS notice here.

Every batch is verified by independent third-party laboratories to ensure consistent quality, purity, and safety.

THIRD-PARTY VERIFIED

PASS

FAIL

Identity Confirmed
99.99% Purity
Heavy Metal Screening
Microbial Safety
Label Potency Verified

Certificates of Analysis (COAs) are available upon request.

02

GMP Compliant

Made in
USA

Third‑Party
Tested

 FDA GRAS

Vegan

Gluten-Free

Scientific Collaborations

Our research includes collaborations with internationally recognized scientists and research institutions, including Professor Barry Halliwell and Temasek Life Sciences Laboratory.

Prof. Barry Halliwell

World-renowned expert in oxidative stress and antioxidant research.

Advancing life science research for better health outcomes.

Clinical Studies

GeneIII’s L-Ergothioneine has been
evaluated in investigator-initiated
human clinical trials registered with
the World Health Organization’s
International Clinical Trials Registry
Platform (ICTRP).

See one of our clinical studies here.

Liver Health

Sleep Quality

Kidney Health

Women’s Health

Precise Dosage

Batch Tested

Quality Checked

GeneIII logo

1909

EGT is first discovered by French chemist Charles Tanret.

Illustration of ergothioneine molecules entering a cell through the OCTN1 transporter

2005

Researchers discover the body’s dedicated transporter for EGT (OCTN1), revealing that the body actively absorbs and retains it.

2021

GeneIII introduced a patented fermentation process to produce EGT at 99.99% purity– the highest on the market. 

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